MPI is led by Prof Hoehn where his research interest focuses on regeneration of cerebral lesions, in particular stroke. He is Head of the in vivo NMR group at the MPI where his goal is to stimulate regeneration through implantation of embryonic stem cells and thereby explore their therapeutic potential. MPI has expertise in developing preclinical stroke models observed under MRI and optical imaging. It has an internationally standing for imaging of stem cell based regeneration processes. 

 

General description Research interest focuses on regeneration of cerebral lesions, in particular stroke.
Staff Expertise Prof Mathias Hoehn’s research interest focuses on regeneration of cerebral lesions, in particular stroke. He is Head of the in vivo NMR group at the Max Planck Institute for Neurological Research where his goal is to stimulate regeneration through implantation of embryonic stem cells and thereby explore their therapeutic potential. His group an international standing for imaging of stem cell based regeneration processes.
Key facilities and infrastructure Magnetic resonance techniques (ESR, ENDOR, NMR);  In-vivo-MRI; Experimental fMRI; Stroke, stem cells, cerebral regeneration set-up; combined suite of molecular imaging techniques
Previous involvement in Research Programmes
  • 6th EU-FP: Networks of Excellence:
    • a) EMIL (European Molecular Imaging Laboratory) 2005-2010 and
    • b) DiMI (Diagnostic Molecular Imaging) 2005-2011. 
  • STREP: StemStroke, 2007-2010
Current Involvement in Research Programmes 7th EU-FP:
  • STREP, ENCITE, 2008-2012
  • STREP, TargetBraIn, 2011-2016
  • STREP, GlowBrain, 2012-2017
Publications
  • Weber, R et al., Journal of Neuroscience, 2008; 28: 1022-1029
  • Ramos-Cabrer, P et al., PLoS One 5, 2010; e12779
  • Aswendt, M et al., NeuroImage, 2012; 62: 1685-1693

News

Publications

Adamczak J. et al. (2015).
Poststroke angiogenesis, Con: Dark side of angiogenesis.
- DOI: 10.1161/STROKEAHA.114.007642
Keuters M. et al. (2015).
Transcranial direct current stiumulation promotes the mobility of engrafted NSCs in the rat brain.
- doi: 10.1002/nbm.3244
Škrášková K. et al. (2015)
Precise anatomical localization of accumulated lipids in Mfp2 deficient murine brains through automated registration of SIMS images to the Allen Brain Atlas.
- doi: 10.1007/s13361-015-1146-6
Tzoumas S. et al.
Spatiospectral denoising framework for multispectral optoacoustic imaging based on sparse signal representation.
- doi: 10.1118/1.4893530
Tzoumas S. et al.
Immune cell imaging using multi-spectral optoacoustic tomography.
- doi: 10.1364/OL.39.003523
Shah D et al. (2015)
Acute modulation of the cholinergic system in the mouse brain detected by pharmacological resting-state functional MRI.
- doi: 10.1016/j.neuroimage.2015.01.009

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Funded by the EC

Project BRAINPATH is supported by, and carried out within the FP7 Programme IAPP, funded by the EC

 

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