Molecular Imaging of Brain Pathophysiology

BRAINPATH aims to build upon current developments in molecular imaging by creating an academic-industrial training and mobility network as the next stage of evolution of imaging technology. Molecular /in vivo/ imaging is a fertile area which harbours a mix of expertise, state-of-art equipment and many different disciplines and inter-sector work environments. Our aim is to train up a new generation of medical imaging scientists so that, within the next 10-15 years, they can bring optical brain imaging to the clinic. The goal is to better understand brain diseases and develop new preclinical treatment strategies so that brain optical imaging will one day be used clinically. It is hoped that in the future it will be implemented as the fourth clinical modality in conjunction with the three already established clinical imaging techniques of magnetic resonance imaging (MRI), x-ray computed tomography (CT) and positron emission tomography (PET).

Our goal is to better understand brain diseases and develop new preclinical imaging strategies. 
Read More
All participants have long standing track records in basic and clinical research 
Read More
Work packages
See detailed description of each working package.
Read More

Addressing Equality

Despite a wealth of female scientists within many institutes, there is still an uphill battle when it comes to gender equality further up the academic ladder. We have a comprehensive plan of action for gender equality in the BRAINPATH project. A number of measures have been put in place to increase the share of female scientists whom are directly involved in the preparation and scientific management of the project. Our intention is for some of our current female postdoctoral scientists will become professorial-level molecular imaging scientists. It is hoped that the experience they will acquire from this project will manifest itself, within the next 10-15 years, as preclinical optical brain imaging being translated into the clinic to enable it to join up as the fourth clinical imaging modality to complement MRI, x-ray CT and PET.

Professor Annemie van der Linden already has a prominent role in this project as Principal Investigator and is on the management and steering committee of this project. Dr Else Tolner and Dr Laura Mezzanotte are part of a new generation of young scientists who are at the cutting-edge of brain imaging research.

Members of the BRAINPATH consortium

Members of the BRAINPATH consortium in attendance at the kick off meeting in Leiden during Autumn 2013Members of the BRAINPATH consortium in attendance at the kick off meeting in Leiden during Autumn 2013



Adamczak J. et al. (2015).
Poststroke angiogenesis, Con: Dark side of angiogenesis.
- DOI: 10.1161/STROKEAHA.114.007642
Keuters M. et al. (2015).
Transcranial direct current stiumulation promotes the mobility of engrafted NSCs in the rat brain.
- doi: 10.1002/nbm.3244
Škrášková K. et al. (2015)
Precise anatomical localization of accumulated lipids in Mfp2 deficient murine brains through automated registration of SIMS images to the Allen Brain Atlas.
- doi: 10.1007/s13361-015-1146-6
Tzoumas S. et al.
Spatiospectral denoising framework for multispectral optoacoustic imaging based on sparse signal representation.
- doi: 10.1118/1.4893530
Tzoumas S. et al.
Immune cell imaging using multi-spectral optoacoustic tomography.
- doi: 10.1364/OL.39.003523
Shah D et al. (2015)
Acute modulation of the cholinergic system in the mouse brain detected by pharmacological resting-state functional MRI.
- doi: 10.1016/j.neuroimage.2015.01.009

Read More

Funded by the EC

Project BRAINPATH is supported by, and carried out within the FP7 Programme IAPP, funded by the EC


Supported by



Contact Us

+31 (0)487-532641
PO Box 217
7500 AE Enschede
The Netherlands
This email address is being protected from spambots. You need JavaScript enabled to view it.